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. 2020 Jul 11;21:476. doi: 10.1186/s12864-020-06874-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Heatmap of -log₁₀(P-value) between pairwise loci located on chromosome 1 in (a) CARe, (b) FBPP, (c) WHI and (d) meta-analysis. Each point represents the -log₁₀(P-value) between two loci. In (a), (b) and (c), if -log₁₀(P-value) is larger than 6, we set the value as 6. In meta-analysis (d), if -log₁₀(P-value) is larger than -log₁₀(significant level), we set the value as 7, which reaches the significant level