Table 3.
Antimicrobial Prevalence by Class in Pediatric and Neonatal Wards
| Pediatric and Neonatal | Overalla,b | PMW and GNMW | HO-PMW | T-PMW | PSW | PICU and NICU | |
|---|---|---|---|---|---|---|---|
| Total number of antimicrobials | 356 | 88 | 70 | 49 | 46 | 103 | |
| Antibiotics, N | 308 (86.5) | 82 | 58 | 26 | 44 | 98 | |
| Antifungals, N | 34 (9.6) | 5 | 10 | 14 | 1 | 4 | |
| Antivirals, N | 13 (3.7) | 1 | 2 | 9 | 0 | 1 | |
| Antituberculosis agents, N | 0 (0) | 0 | 0 | 0 | 0 | 0 | |
| Other, N | 1 (0.3) | 0 | 0 | 0 | 1 | 0 | |
| Antibiotics by Class, N | |||||||
| Penicillins with β-lactamase inhibitors | 31 (10.1) | 8 | 8 | 9 | 3 | 3 | |
| Penicillins with extended spectrum | 44 (14.3) | 12 | 3 | 1 | 4 | 24 | |
| β-lactamase-resistant penicillins | 4 (1.3) | 2 | 2 | ||||
| β-lactamase-sensitive penicillins | 1 (0.3) | 1 | |||||
| 1st generation cephalosporins | 30 (9.7) | 12 | 2 | 2 | 8 | 6 | |
| 2nd generation cephalosporins | 6 (1.9) | 4 | 1 | 1 | |||
| 3rd generation cephalosporins | 52 (16.9) | 19 | 4 | 4 | 5 | 20 | |
| Carbapenems | 8 (2.6) | 1 | 2 | 1 | 4 | ||
| Fluoroquinolones | 10 (3.2) | 3 | 5 | 2 | 0 | 0 | |
| Aminoglycosides | 29 (9.4) | 3 | 2 | 5 | 19 | ||
| Macrolides | 4 (1.3) | 2 | 1 | 1 | |||
| Tetracyclines | 1 (0.3) | 1 | |||||
| Clindamycin | 7 (2.3) | 1 | 6 | ||||
| Metronidazole | 14 (4.5) | 3 | 3 | 5 | 3 | ||
| Combinations of sulfonamides and trimethoprim | 40 (13.0) | 6 | 22 | 3 | 3 | 6 | |
| Vancomycin PO | 3 (1.0) | 1 | 1 | 1 | |||
| Vancomycin IV | 23 (7.5) | 5 | 4 | 4 | 2 | 8 | |
| Rifamycins | 1 (0.3) | 1 | |||||
a Numbers in parentheses represent a percentage
b The denominator to calculate percentages for each antibiotic subclass is the total number of antibiotics
Abbreviations: GNMW general neonatal medical ward, HO-PMW hematology-oncology PMW, NICU neonatal intensive care unit, PICU pediatric intensive care unit, PMW pediatric medical ward, PSW pediatric surgical ward, T-PMW transplant-PMW