Table 4.
Groups | CAE-A (n = 60) (age ≤ 50) | CAE-B (n = 83) (50 < age ≤ 70) | CAE-C (n = 74) (age > 70) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pretreatment | Posttreatment | Delta | p-value | Pretreatment | Posttreatment | Delta | p-value | Pretreatment | Posttreatment | Delta | p-value | |
hs-CRP (mg/L) | 32.3 ± 5.51 | 17.5 ± 2.38 * | 15.1 ± 3.3 | 0.0001 | 26.1 ± 4.23 | 18.8 ± 2.74 * | 9.4 ± 2.86 | 0.023 | 22.5 ± 4.82 | 19.8 ± 2.98 | 4.5 ± 3.12 | 0.310 |
IL-6 (pg/dL) | 12.3 ± 1.5 | 6.4 ± 1.7* | 5.9 ± 1.6 | 0.021 | 10.9 ± 1.3 | 7.5 ± 2.0* | 3.0 ± 1.5 | 0.043 | 8.9 ± 1.1 | 7.6 ± 2.3 | 1.9 ± 1.5 | 0.519 |
CAE coronary artery ectasia, hs-CRP high-sensitivity C-reactive protein, IL-6 interleukin-6. Pretreatment: values measured at study inclusion. Posttreatment: values measured after 6 months of treatment with rosuvastatin. *: p < 0.05 vs corresponding pretreatment group