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. 2020 Jul 11;20:330. doi: 10.1186/s12872-020-01604-z

Table 4.

Comparison of serum hs-CRP and IL-6 levels in CAE patients treated with rosuvastatin

Groups CAE-A (n = 60) (age ≤ 50) CAE-B (n = 83) (50 < age ≤ 70) CAE-C (n = 74) (age > 70)
Pretreatment Posttreatment Delta p-value Pretreatment Posttreatment Delta p-value Pretreatment Posttreatment Delta p-value
hs-CRP (mg/L) 32.3 ± 5.51 17.5 ± 2.38 * 15.1 ± 3.3 0.0001 26.1 ± 4.23 18.8 ± 2.74 * 9.4 ± 2.86 0.023 22.5 ± 4.82 19.8 ± 2.98 4.5 ± 3.12 0.310
IL-6 (pg/dL) 12.3 ± 1.5 6.4 ± 1.7* 5.9 ± 1.6 0.021 10.9 ± 1.3 7.5 ± 2.0* 3.0 ± 1.5 0.043 8.9 ± 1.1 7.6 ± 2.3 1.9 ± 1.5 0.519

CAE coronary artery ectasia, hs-CRP high-sensitivity C-reactive protein, IL-6 interleukin-6. Pretreatment: values measured at study inclusion. Posttreatment: values measured after 6 months of treatment with rosuvastatin. *: p < 0.05 vs corresponding pretreatment group