Table 5.
Resources for studying the effect of mutations on kinases and phosphorylation sites
| Tool | Last update | Version | Prediction type | Method | Kinases | Method of access | References |
|---|---|---|---|---|---|---|---|
| PhosSNP | 2009 | 1.0 | SNVs that might influence phosphorylation status | Rules | Tool | [89] | |
| MIMP | 2015 | Missense SNV impact on kinase-substrate | Bayesian model | 322 | Web|DL|Tool | [91] | |
| ReKINect | 2015 | Effect of SNV on signaling network | PSSM | Web|DL | [92] | ||
| PhosphoPICK-SNP | 2016 | Effect of SNV on phosphorylation level | Bayesian models | 107 | Web|DL | [93] | |
| ActiveDriverDB | 2017 | Somatic variants affecting phosphorylation | Rules | 322 | Web|DL | [90] |
SNV single nucleotide variation, PSSM position specific scoring matrix