Table 7.
Visualization, data retrieval, and prediction tools
| Tool | Last update | Version | Type | Input | Output | Method of access | References |
|---|---|---|---|---|---|---|---|
| CPhos | 2012 | 1.3 | Phosphorylation site conservation | Phosphopeptides | Conservation scores | Tool | [101] |
| PhosphoLogo | 2012 | Visualization of sequence motifs | Sequence motifs | Motif visualization | Tool | [98] | |
| RegPhos2.0 | 2013 | 2.0 | Visualization of kinase data | Gene names | Network visualization or cancer gene expression | Web|DL | [42, 113] |
| eFIP | 2014 | Returns publications involving phosphorylation | Gene names or words | Publications matching those words | Web | [100] | |
| RLIMS-P | 2014 | 2.0 | returns protein phosphorylation information from literature | PMIDs or keywords | kinase, substrate, and site | Web|DL | [99] |
| PyTMs | 2015 | 1.2 | pyMOL plugin to add PTMs to protein models | Protein models, PTMs | PTMs integrated in protein models | Tool | [102] |
| 14-3-3-Pred | 2015 | Predicts 14-3-3 binding phosphosite | Protein sequences | Predicted 14-3-3 binding sites | Web|DL | [103] | |
| KinMap | 2016 | Kinome tree visualization | Kinases | Tree with highlighted branches | Web|DL | [97] | |
| KinConform | 2017 | Determines which structures are kinases | Structures | Active or inactive kinase chains | Tool | [96] | |
| Kinannote | 2017 | 1.0 | Classifies sequences as kinases | Protein sequences | Kinase annotation | Tool | [95] |