Table 7.
Prevalence of dhfr and dhps haplotypes in Plasmodium falciparum isolates from Lagos, Nigeria
| Gene | Category | Haplotype | n (%) |
|---|---|---|---|
| dhfr | Wild type | CNCSI | 8 (3.3) |
| Double mutation | CICNI | 1 (0.4) | |
| CNRNI | 3 (1.2) | ||
| Triple mutation | CIRNI | 227 (93.8) | |
| Quadruple mutation | CIRNIR | 1 (0.4) | |
| CIRNIK | 1 (0.4) | ||
| CIRNIE | 1 (0.4) | ||
| dhps | Single mutation | SGKAA | 74 (44.3) |
| AAKAA | 4 (2.4) | ||
| Double mutations | AGKAA | 7 (4.2) | |
| FAKAS | 3 (1.8) | ||
| SGKGA | 2 (1.2) | ||
| AAKGA | 1 (0.6) | ||
| SGKAS | 6 (3.6) | ||
| SGEAA | 2 (1.2) | ||
| VSGKAA | 1 (0.6) | ||
| Triple mutations | SGKGS | 9 (5.4) | |
| VAGKAA | 1 (0.6) | ||
| AGKGA | 1 (0.6) | ||
| AGKAS | 14 (8.4) | ||
| Quadruple | AGKGS | 2 (1.2) | |
| VAGKAS | 3 (1.8) | ||
| VAGKGA | 4 (2.4) | ||
| Quintuple | VAGKGS | 33 (19.8) |
Mutations in the haplotype are underlined.