Fig. 3.

Pathogenicity induced by PEDV infection. (A) Kinetics of viral shedding in a different age of piglets. The viral loads in anal swabs at indicated time points were analyzed by real-time RT-qPCR. LD line was the maximum value from blank control detected by RT-qPCR. (B) Fecal wet/dry ratios for each age group were calculated to evaluate the severity of diarrhea. (C) H&E staining of different segments of the small intestine from different age groups. Solid arrows indicate the detachment of intestinal epithelial cells. Empty arrows represent cellulosic exudation. Triangle means vascular congestion.