Table 1.
Postnatal Functional Outcomes and Spinal Angulation by Treatment
All Animals (n=31) | ECM only (n=10) | PMSC-ECM (n=21) | p value | |
---|---|---|---|---|
SLR Score | 14 (7.5-15) | 7.5 (4.3-12) | 15 (13-15) | 0.026 |
Lumbar Level of Angulation | 2.5 (2-3.5) | 2 (2-2.5) | 2.5 (2.5-3.5) | 0.025 |
Degree of Angulation | 24.3 (16.3-34.8) | 29.9 (15.7-49.9) | 24.3 (16.7-33.0) | 0.516 |
Lamina Cross-sectional Area (% of Normal) | 22.5 (15.2-29.5) | 20.5 (14.6-25.3) | 25.0 (15.9-33.0) | 0.363 |
All values presented as median (IQR). Treatment groups (ECM only and PMSC-ECM) were compared with the Mann-Whitney U test.
ECM, extracellular matrix; PMSC-ECM, ECM seeded with placental mesenchymal stromal cells; SLR, Sheep Locomotor Rating; IQR, interquartile range.