Table 2.
Distribution of genotype and allele frequencies of tumor necrosis factor-alpha-308 G>A among case and control population
| COPD patients (n=100), n (%) |
Controls (n=163), n (%) |
OR (95% CI) | P | |
|---|---|---|---|---|
| Genotype | ||||
| GG | 91 (91) | 150 (92) | 1.0 (reference) | |
| GA | 9 (9) | 13 (8) | 1.14 (0.46-2.7) | 0.82 |
| AA | 0 | 0 | ||
| GA + AA | 9 (9) | 13 (7.9) | 1.14 (0.46-2.7) | 0.82 |
| Allele | ||||
| G | 191 (95.5) | 313 (96) | 1.0 (reference) | |
| A | 9 (4.5) | 13 (3.9) | 1.13 (0.47-2.7) | 0.77 |
ORs (95% CIs) were obtained from conditional logistic regression models. P values calculated using Chi-square tests. n: Number of subjects or individuals, G: Guanine, A: Adenine, CIs: Confidence intervals, ORs: Odds ratios, COPD: Chronic obstructive pulmonary disease