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. Author manuscript; available in PMC: 2021 Apr 7.
Published in final edited form as: Anal Chem. 2020 Mar 24;92(7):5311–5318. doi: 10.1021/acs.analchem.9b05853

Table 2.

Example of results from a sputum-to-genotype run on the system. The first sample is a DNA-to-genotype external positive control.

Sample H37Ra DNA, 1 pg 1200 CFU/ml 400 CFU/ml 130 CFU/ml 43 CFU/ml Negative sputum
MTB present wild type MTB present wild type MTB present wild type MTB present wild type MTB present wild type MTB Absent
Test Validity VALID VALID VALID VALID VALID VALID
M. tuberculosis Complex PRESENT PRESENT PRESENT PRESENT PRESENT Absent
Rifampin Resistance Not Detected Not Detected Not Detected Not Detected Not Detected N/A
Isoniazid Resistance Not Detected Not Detected Not Detected Not Detected Not Detected N/A