Figure 6.

(a) Glomerulosclerosis is significantly increased in SLE mice at 28 weeks of age compared to age‐matched vehicle‐ and curcumin‐treated control mice (*p < .001 versus control, two‐way ANOVA, group effect). Curcumin‐treated SLE mice had less glomerulosclerosis compared to vehicle‐treated SLE mice at 28 weeks of age (^# p < .001). (b) Glomerulosclerosis is significantly increased at 34 weeks of age in SLE mice compared to age‐matched control mice (*p < .001 versus control, two‐way ANOVA, group effect). Glomerulosclerosis is significantly decreased at 34 weeks of age in curcumin‐treated SLE mice compared to age‐matched vehicle treated SLE mice,*p = .05. (c–j) Representative pictures of glomerulosclerosis (40x) from paraffin‐embedded kidneys stained with hematoxylin and eosin