Table 2:

Factors associated with presence of PIPs, logistic regression analysis

		Univariable			Multivariable**
Variable	PIPs (%)	OR	95% CI	P value*	aOR	95%	P value*
Patients with PIPs, n(%)	462 (100)
Age at IBD diagnosis	-	1.00	0.99 – 1.01	0.96
Male sex	238 (51)	1.09	0.88 – 1.36	0.42
Extensive disease	396 (88)	1.51	1.09 – 2.08	0.01	1.92	1.34 – 2.74	<0.0005
USA cohort#	140 (30)	1.25	0.98 – 1.59	0.06	1.40	1.04 – 1.88	0.03
Mean histologic inflammation^	-	1.39	1.21 – 1.60	<0.0005	1.32	1.13 – 1.55	0.001
Primary sclerosing cholangitis	38 (8.2)	0.42	0.29 – 0.61	<0.0005	0.38	0.26 – 0.55	<0.0005
Crohn’s disease##	170 (37)	1.06	0.84 – 1.32	0.64
Disease duration at time of index colonoscopy	-	1.01	1.00 – 1.02	0.13

^*Significant at P <0.05 level. PIPs: Post-inflammatory polyps.

^#Reference category: Dutch cohort;

^{^}Prior to the first reported PIP;

^##Reference category: ulcerative colitis/IBD-unclassified.

^**Note: 77 patients (15 with PIPs) were excluded due to missing data.