Table S3. Associations of the first 10 principal components and OS of NSCLC in the PLCO trial (n=1,185).
| PC* | Parameter estimate | Standard error | Chi-square | P |
|---|---|---|---|---|
| PC1 | 4.821 | 1.353 | 12.697 | <0.001 |
| PC2 | −0.681 | 1.228 | 0.308 | 0.579 |
| PC3 | −3.054 | 0.949 | 10.351 | 0.001 |
| PC4 | −2.837 | 1.246 | 5.184 | 0.023 |
| PC5 | −0.910 | 1.232 | 0.546 | 0.460 |
| PC6 | 1.355 | 1.252 | 1.172 | 0.279 |
| PC7 | −0.236 | 1.218 | 0.038 | 0.846 |
| PC8 | −1.684 | 1.322 | 1.622 | 0.203 |
| PC9 | −1.886 | 1.267 | 2.216 | 0.137 |
| PC10 | 0.347 | 1.240 | 0.078 | 0.180 |
*, the first 4 were used for the adjustment for population stratification in the multivariate analysis. OS, overall survival; NSCLC, non-small cell lung cancer; PLCO, the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial; PC, principal component.