Table 5.
Coefficients (and their p-value) for multiple linear regressions between explanatory variable(s) and the ultimate compressive force of L6 VBs with and without 2 categorical covariates (Cvar) including interactions (p<0.06). N=76 mice
| Explanatory variables | Model: | Referencea | Coefficient 1b | Coefficient 2c | Cvard | Intere | Adj-R2 | |||
|---|---|---|---|---|---|---|---|---|---|---|
| H-μFEA+Age | 6-mo.: | +10.9 | (p=0.261) | +0.7 | (p=0.018) | – | – | (p=0.005) | (P=0.007) | 0.4578 |
| 20-mo.: | −28.6 | +1.8 | ||||||||
| I-μEA+Age | 6-mo.: | +19.3 | (p=0.001) | +0.5 | (p=0.018) | – | – | (P=0.005) | (P=0.015) | 0.3911 |
| 20-mo.: | −9.8 | +1.5 | ||||||||
| BV/TV g | All: | +2.5 | (p=0.656) | +133.7 | (p<0.0001) | – | – | NI | NI | 0.4067 |
| Tb.vBMD+Sex | F: | +2.1 | (p=0.707) | +0.1 | (p<0.0001) | – | – | (P=0.023) | NI | 0.3972 |
| M: | −2.0 | |||||||||
| Tb.N+Age+Sexf | F/6-mo.: | +0.64 | +9.26 | (p=0.074) | (P=0.026) | 0.1976 | ||||
| F/20-mo.: | +7.04 | |||||||||
| M/6-mo.: | +41.83 | −1.59 | ||||||||
| M/20-mo.: | +35.03 | (p=0.007) | ||||||||
| B.Ar+Age | 6-mo.: | +11.9 | (p=0.195) | +33.5 | (P = 0.016) | – | – | (P=0.017) | (P=0.030) | 0.4062 |
| 20-mo.: | −20.2 | +80.0 | ||||||||
| Sh. Th | All: | +13.9 | (p=0.128) | +255.3 | (p=0.048) | – | – | NI | NI | 0.0559 |
| Tb.vBMD+B.Ar | All: | −8.0 | (p=0.267) | +0.064 | (p=0.015) | +35.0 | (p=0.028) | NI | NI | 0.3985 |
As the intercept term in the GLM, the reference value is always included even if it is not significant. There are 2 reference values when one of the covariates is in included in the regression model.
Coefficient 1 belongs to the first explanatory variable in the model (first column). There are 2 values when the variable interacts with one of the covariates.
Coefficient 2 belongs to the second explanatory variable if included in the model. There are 2 values when the variable interacts with one of the covariates.
Sex or age group is the second or third explanatory variable depending on the model. In some regressions, it was not included (NI) in the GLM because it was removed due to a lack of significance.
An interaction term was included in the model when significant. Otherwise, it was removed.
There is a significant interaction between sex and age of the animal as well as between sex and Tb.N.
Tb.N, B.Ar, and Sh.Th do not help BV/TV explain the variance in VB strength (ultimate force).