Table 1.
Baseline characteristics of patients in ACEI/ARB and non-ACEI/ARB groups before and after propensity score matching
| Unmatched |
Matched |
|||||
|---|---|---|---|---|---|---|
| ACEI/ARB | Non-ACEI/ARB | p value | ACEI/ARB | Non-ACEI/ARB | p value | |
| n = 78 | n = 512 | n = 78 | n = 71 | |||
| Variables | ||||||
| Age (years), median (IQR) | 63 (55-75) | 42 (32-55) | <0.001 | 65 (55-75) | 64 (51-77) | 0.658 |
| Age >60 years | 51 (66.2%) | 99 (19.3%) | <0.001 | 77 (98.7%) | 68 (95.8%) | 0.348 |
| Men | 46 (59.7%) | 242 (47.1%) | 0.051 | 47 (60.3%) | 36 (50.7%) | 0.253 |
| Number of comorbidities, median (IQR) | 3 (3-4) | 1 (0-2) | <0.001 | 3 (3-4) | 3 (2-4) | 0.041 |
| Coronary Artery Disease | 15 (19.5%) | 16 (3.2%) | <0.001 | 16 (20.5%) | 10 (14.1%) | 0.388 |
| Myocardial infarction | 7 (9.1%) | 5 (1.1%) | <0.001 | 8 (10.3%) | 3 (4.3%) | 0.217 |
| Percutaneous Coronary Intervention/Coronary Artery Bypass Grafting | 13 (17.9%) | 11 (2.2%) | <0.001 | 13 (14.8%) | 7 (9.9%) | 0.472 |
| Peripheral Arterial Disease | 5 (8.3%) | 6 (1.4%) | 0.005 | 6 (7.7%) | 4 (5.6%) | 0.748 |
| Stroke/Transient Ischemic Attack | 9 (15%) | 10 (2.2%) | <0.001 | 9 (11.7%) | 7 (9.9%) | 0.795 |
| Cardiomyopathy | 8 (10.5%) | 9 (1.8%) | <0.001 | 9 (11.7%) | 4 (5.7%) | 0.203 |
| Heart failure | 7 (15.6%) | 14 (4.3%) | 0.008 | 10 (12.8%) | 8 (11.3%) | 0.807 |
| Heart failure with reduced ejection fraction | 3 (9.1%) | 5 (2.2%) | 0.064 | 4 (11.8%) | 3 (7.3%) | 0.695 |
| Left ventricle ejection fraction, median (IQR) | 63 (58-68) | 63 (58-65) | 0.704 | 63 (54-67) | 65 (58-66) | 0.878 |
| Atrial Fibrillation | 8 (12.7%) | 15 (3.2%) | <0.001 | 8 (12.5%) | 9 (12.9%) | 0.979 |
| Other atrial/ventricular arrhythmias | 3 (5.1%) | 12 (2.6%) | 0.215 | 3 (4.8%) | 6 (8.6%) | 0.498 |
| Permanent pacemaker or Implantable Cardioverter Defibrillator | 5 (8.3%) | 2 (0.5%) | <0.001 | 5 (8.2%) | 2 (3.1%) | 0.262 |
| Hypertension | 73 (96.1%) | 77 (15.7%) | <0.001 | 74 (96.1%) | 63 (88.7%) | 0.119 |
| Dyslipidemia | 51 (67.1%) | 145 (29.7%) | <0.001 | 66 (84.6%) | 56 (78.9%) | 0.472 |
| Diabetes/Pre-diabetes | 41 (53.9%) | 114 (23.2%) | <0.001 | 41 (52.6%) | 40 (56.3%) | 0.742 |
| Smoking, current or past | 11 (15.9%) | 64 (13.4%) | 0.363 | 13 (14.8%) | 18 (25.4%) | 0.112 |
| Obesity | 26 (36.6%) | 88 (18.3%) | 0.001 | 30 (34.1%) | 19 (26.8%) | 0.388 |
| Hypothyroidism | 16 (21.1%) | 33 (6.8%) | <0.001 | 17 (22.1%) | 11 (15.7%) | 0.402 |
| Chronic lung disease | 15 (19.7%) | 50 (10.3%) | 0.011 | 15 (19.5%) | 13 (18.3%) | 0.732 |
| Obstructive Sleep Apnea | 11 (17.5%) | 19 (4.1%) | <0.001 | 11 (17.2%) | 6 (8.6%) | 0.134 |
| Chronic Kidney Disease/End Stage Renal Disease | 14 (18.4%) | 25 (5.1%) | <0.001 | 15 (19.5%) | 14 (19.7%) | 0.991 |
| Organ Transplantation | 5 (6.8%) | 9 (1.9%) | 0.028 | 5 (6.7%) | 4 (5.8%) | 0.994 |
| Deep Vein or Pulmonary Thromboembolism | 4 (6.2%) | 15 (3.3%) | 0.11 | 4 (6.2%) | 6 (8.8%) | 0.997 |
| Cancer | 15 (19.7%) | 22 (4.5%) | <0.001 | 15 (19.5%) | 6 (8.5%) | 0.063 |
| Active Cancer | 2 (2.8%) | 5 (1.1%) | 0.215 | 2 (2.9%) | 1 (1.6%) | 0.972 |
| Immunologic diseases | 2 (3.3%) | 16 (3.5%) | 0.978 | 2 (3.2%) | 4 (6.1%) | 0.681 |
| Hematologic diseases | 7 (11.3%) | 14 (3.1%) | 0.007 | 7 (11.1%) | 6 (8.8%) | 0.773 |
| Rheumatologic diseases | 7 (11.5%) | 17 (3.7%) | 0.015 | 7 (11.3%) | 4 (5.8%) | 0.348 |
IQR = interquartile range.