Table 1. Studies (more than 50 cases) on radiotherapy for nmCRPC.
Author, year | Total no. | No. of N0/N1 | RT dose (Gy) | Median follow-up (m) | Outcomes |
---|---|---|---|---|---|
White et al. (16), 2015 | 51 | 51/0 | 50 | 54 | 3y FFLF: 85%; 5y FFLF: 81%; 5y CSS: 65%; 5y OS: 35% |
Akimoto et al. (17), 2003 | 53 | 53/0 | 69 | 35 | 3y CSS: 94%; 3y CFFS: 78%; 5y CSS: 87%; 5y CFFS: 56% |
Sasaki et al. (18), 2009 | 140 | 84/28 | 66 | 20.7 | 5y OS: 48.1%; 5y CPFS: 36.7% |
Ogawa et al. (19), 2008 | 84 | 58/10 | 66 | 26.9 | 3y OS: 67%; 3y LCR: 93%; 3y PFS: 61% |
Nakamura et al. (20), 2004 | 61 | 45/15 | 60 | 17 | 5y OS: 51.6%; 5y PFS: 43.5% |
m, month; y, year; FFLF, free from local failure; CSS, cancer-specific survival; OS, overall survival; CFFS, clinical failure-free survival; RT, radiotherapy; LCR, locoregional control rate; CPFS, clinical progression-free survival; PFS, progression-free survival.