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. 2020 Jun;9(3):1232–1243. doi: 10.21037/tau.2020.03.45

Table 2. Subgroup analysis of CKD group.

Factors Overall (n=26) AKI (n=14) No AKI (n=12) P value
Baseline characteristics
   Age (years) 67.46±8.10 68.21±7.81 66.58±8.70 0.619
   Male 22 (84.62%) 13 (92.86%) 9 (75.00%) 0.208
   Female 4 (15.38%) 1 (7.14%) 3 (25.00%)
   BMI (kg/m2) 23.55 (23.00, 24.95) 23.38 (22.99, 24.68) 23.69 (22.93, 25.78) 0.595
   Tobacco use 8 (30.77%) 5 (35.71%) 3 (25.00%) 0.555
   Alcohol use 4 (15.38%) 2 (14.29%) 2 (16.67%) 0.867
Preoperative factors
   Hypertension 13 (50.00%) 8 (57.14%) 5 (41.67%) 0.431
   MAP (mmHg) 95.56±10.12 96.43±10.07 94.56±10.54 0.649
   Diabetes 4 (15.38%) 3 (21.43%) 1 (8.33%) 0.888
FBG (mmol/L) 5.55±1.39 5.66±1.71 5.43±0.97 0.685
   SCr (μmol/L) 124.50 (113.74, 138.38) 124.50 (116.26, 147.00) 120.75 (110.64, 138.61) 0.432
   eGFR (mL/min/1.73 m2) 47.63±9.96 45.39±12.23 50.24±5.89 0.223
   Hb (g/L) 132.27±17.94 123.79±18.28 142.17±11.76 0.006*
   ALB (g/L) 41.05±4.08 39.29±4.11 43.12±3.05 0.014*
   K+ (mmol/L) 4.09±0.46 4.11±0.54 4.07±0.37 0.847
   BUN (mmol/L) 7.69 (6.50, 8.60) 6.66 (5.35, 7.77) 6.07 (5.26, 7.68) 0.820
   R.E.N.A.L score 7.00 (6.00, 8.25) 4.00 (2.00, 6.25) 5.00 (3.00, 6.75) 0.095
   CCI 5.00 (3.00, 6.25) 3.00 (1.00, 4.00) 3.00 (1.00, 4.00) 0.347
Intraoperative factors
   Surgical approach
      Open 14 (53.85%) 11 (78.57%) 3 (25.00%) 0.006*
      Laparoscopic 12 (46.15%) 3 (21.43%) 9 (75.00%)
   Surgery time (min) 112.50 (64.00, 180.25) 148.25 (102.75, 188.25) 62.00 (52.50, 115.75) 0.004*
   Ischemia time (min) 20.00 (15.00, 23.25) 20.50 (19.50, 25.25) 15.00 (8.50, 21.25) 0.036*
   Type of ischemia
      Warm 1246.15%) 6 (42.86%) 6 (50.00%) 0.561
      Cold 13 (50.00%) 8 (57.14%) 5 (41.67%)
   Intraoperative fluid
      Crystalloid (mL) 1225.00 (1100.00, 1762.50) 1412.50 (1225.00, 1762.50) 1100.00 (912.50, 1925.00) 0.060
      Colloid (mL) 0.00 (0.00, 0.00) 0.00 (0.00, 500.00) 0.00 (0.00, 0.00) 0.131
      Total fluid (mL) 1600.00 (1100.00, 1812.50) 1672.50 (1225.00, 1862.50) 1100.00 (912.50, 1925.00) 0.060
      Units transfused (mL) 0.00 (0.00, 0.00) 0.00 (0.00, 0.00) 0.00 (0.00, 0.00) 1.000
      Mannitol (mL) 50.00 (0.00, 125.00) 122.50 (0.00, 125.00) 0.00 (0.00, 75.00) 0.060
   Tumor maximum diameter (cm) 3.07 (1.82, 4.02) 3.41 (1.86, 5.70) 2.62 (1.66, 3.21) 0.087
   Multifocality 7 (26.92%) 4 (28.57%) 3 (25.00%) 0.838

Continuous variables are presented as medians with quartiles or means with standard deviation. Frequencies with proportions are displayed for categorical variables. The number in parenthesis represents the number of patients with available data. *P<0.05. BMI, body mass index; MAP, mean arterial pressure; FBG, fasted blood glucose; CKD, chronic kidney disease; SCr, serum creatinine; eGFR, estimated glomerular function rate; Hb, hemoglobin; ALB, albumin; BUN, blood urea nitrogen; CCI, Charlson comorbidity index; RRT, renal replacement therapy; ICU, intensive care unit.