Table 6. Effects of engraftment environment on tumor take rate.
Variables | Number of patients | Number of mice | Tumor take rate %* [n] | P value |
---|---|---|---|---|
Mouse strain | ||||
BALB/c nude | 11 | 36 | 55% [6] | 0.1294 |
NOG | 2 | 4 | 50% [1] | 0.7172 |
SCID | 2 | 3 | 0% | 0.2078 |
Hairless | 2 | 9 | 0% | 0.2078 |
Hormone supplementation in BALB/c nude mice | ||||
No | 7 | 16 | 86% [6] | 0.0261 |
Te | 4 | 20 | 0% |
Total number of patients was 17. *, tumor take rate was defined as percent of patients with carcinoma in validation sample who developed at least one histologically validated tumor.