Table 3.

Subgroup analyses of ITP patients

Assay	Treated	Not treated	P value	Splenectomized	Not splenectomized	P value
Mean serum C3, mg/dL (95% CI)	103.8 (93.2‐114.3)	104.7 (96.9‐112.5)	.90	120.6 (92.2‐148.9)	101.0 (95.2‐106.8)	.035
Mean serum C4, mg/dL (95% CI)	18.1 (15.0‐21.2)	23.1 (18.3‐27.8)	.04	21.6 (14.0‐29.3)	20.2 (17.2‐23.2)	.952
Mean serum CH50, U/mL (95% CI)	50.4 (43.7‐57.2)	63.0 (59.2‐66.9)	.004	55.0 (44.3‐65.6)	56.6 (52.1‐61.2)	.667

Comparison of complement assay results in patients with ITP requiring treatment (N = 56) versus patients with ITP not requiring treatment (N = 52) and splenectomized patients with ITP (N = 17) versus nonsplenectomized patients with ITP (N = 91). Groups compared with Wilcoxon rank‐sum test.

Abbreviations: CI, confidence interval; ITP, immune thrombocytopenia.