Fig.4. Expression of the 16-gene ACS signature genes across species.
(A) Ortholog gene expression of 13 out of 16 human ACS signature genes (7) in progressor versus controller, progressor versus naive and controller versus naive, in mouse and macaque. Note that both FCGR1A and FCGR1B are represented by a single gene in mice and macaques, and human ETVTs ortholog in mouse is called Etv6. (B) SCARF1 expression in progressor, controller versus naive in mouse and macaque is shown. (C) SEPT4 expression in progressor, controller and naive is shown in mouse and macaque. All P values shown on the expression swarm plots represent FDR-corrected significance values for differential expression calculated by DESeq2.