Table 1.
The results of β-N-methylamino-L-alanine (BMAA) effect on the protein profile of Nostoc during growth in a nitrogen-replete medium. The number of upregulated and downregulated proteins is quantified according to label-free quantification (LFQ) ratio of BMAA-treated sample/Control sample.
| No. | Pathway | Number of Proteins Affected by BMAA | Total Amount | |
|---|---|---|---|---|
| Upregulated | Downregulated | |||
| 1 | Nitrogen metabolism | 2 | 1 | 1 |
| 2 | Photosynthesis | 7 | 2 | 5 |
| 3 | CO2 fixation and CO2-concentrating mechanism | 7 | 3 | 4 |
| 4 | Cell division | 2 | 0 | 2 |
| 5 | Regulatory proteins, proteases | 10 | 5 | 4 |
| 6 | Transporters | 2 | 2 | 0 |
| 7 | Stress response | 6 | 5 | 1 |
| 8 | Translation | 7 | 5 | 2 |
| 9 | Amino acid synthesis and metabolism | 10 | 5 | 5 |
| 10 | Purine and Pyrimidine metabolism | 4 | 2 | 2 |
| 11 | Starch and sucrose metabolism | 2 | 2 | 0 |
| 12 | Sulfur metabolism | 1 | 0 | 1 |
| 13 | Fatty acid biosynthesis | 1 | 1 | 0 |
| 14 | Energy metabolism | 2 | 1 | 1 |
| 15 | Hypothetical proteins | 18 | 10 | 8 |
| Total | 80 | 44 | 36 | |