Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 4;12(6):373. doi: 10.3390/toxins12060373

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme depicting the development of the diverse blood cells of the hematopoietic system that takes place in the bone marrow. Hematopoiesis starts from pluripotent hematopoietic stem cells (HSC). The erythroid and myeloid lineages originate from CD34⁺ hematopoietic stem/progenitor cells (HSPC). Differentiation (from left to right) of erythrocytes, megakaryocytes (platelet-forming cells), granulocytes (neutrophilic, eosinophilic, and basophilic, from left to right), monocytes (which further differentiate in tissues to adherent macrophages and/or dendritic cells), and small lymphocytes (T and B lymphocytes) as well as natural killer cells (large granular lymphocytes) representing the main groups of blood cells. IE, immature erythroblast (proerythroblast); BE, basophilic erythroblast; PE, polychromatophilic erythroblast; OE, orthochromatophilic erythroblast; R, reticulocyte. The figure was adapted from SERVIER MEDICAL ART (https://smart.servier.com) and modified in parts.