Table 3.
HBV virologic response to lamivudine-based ART over 12 months of follow-up.
| ID | HIV RNA | Baseline | 6-month follow-up | 12-month follow-up | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Month 6 | Month 12 | HBsAg | Anti-HBs | Anti-HBc | HBV DNA | HBV DNA | HBsAg | Mutation | HBV DNA | HBsAg | Mutation | ||
| ZA053 | ND | ND | − | + | − | TND | 7.45 × 101 | − | <6.00 × 100 | − | ||||
| ZA265 | 410,000 | <50 | <50 | + | − | - | >1.10 × 108 | 7.36 × 102 | + | 1.52 × 105 | + | |||
| ZA320 | 171,533 | <50 | <50 | − | − | + | >1.10 × 108 | 1.05 × 104 | + | A181T | >1.10 × 108 | ND | ||
| ZA345 | 62,000 | <50 | <50 | − | − | − | 1.58 × 102 | <6.00 × 100 | − | 7.5 × 100 | − | |||
| ZA113 | 750,000 | 147 | <50 | + | − | + | 1.99 × 104 | 2.23 × 105 | ND | 8.76 × 103 | ND | L180M | ||
| ZA156 | 29,000 | <50 | <50 | − | + | − | TND | TND | − | 4.09 × 102 | − | |||
| ZA117 | ND | <25 | 55 | + | − | − | 7.94 × 104 | 7.5 × 100 | − | 5.73 × 102 | − | |||
| ZA177 | 23,000 | ND | ND | − | − | + | 3.61 × 101 | <6.00 × 100 | + | 9.68 × 100 | ND | |||
| ZA024 | 51,000 | 74,784 | ND | − | + | + | 4.46 × 103 | <6.00 × 100 | − | >6.00 × 100 | − | |||
| ZA013 | 97,000 | <50 | <50 | − | + | + | 2.95 × 102 | TND | − | TND | − | |||
| ZA467 | ND | ND | ND | + | − | − | 3.10 × 101 | <6.00 × 100 | ND | TND | ND | |||
| ZA131 | 642,499 | <50 | <50 | + | − | − | TND | 3.39 × 102 | + | M204I | >1.10 × 108 | + | ||
| ZA047 | 97,000 | <50 | <50 | − | − | − | TND | 1.10 × 103 | − | TND | − | |||
| ZA217 | ND | ND | ND | − | − | + | 1.14 × 106 | TND | ND | 1.10 × 101 | ND | |||
| ZA540 | ND | 220 | <50 | − | + | + | 2.40 × 102 | TND | − | TND | ND | |||
| ZA251 | 25,000 | <50 | <50 | + | − | − | 3.40 × 102 | <6.00 × 100 | − | TND | ND | |||
| ZA212 | ND | ND | ND | + | − | − | TND | TND | ND | TND | ND | |||
| ZA024 | 438,585 | ND | ND | + | − | + | >1.10 × 108 | 7.58 × 103 | ND | M204I | >1.10 × 108 | ND | ||
| ZA064 | 213,140 | <50 | <50 | − | − | + | <6.00 × 100 | TND | ND | 3.45 × 101 | ND | |||
| ZA348 | ND | ND | ND | + | − | − | 2.74 × 101 | TND | ND | 2.81 × 101 | ND | |||
ND = not done; TND = target not detected.