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. 2020 Jun 10;12(6):630. doi: 10.3390/v12060630

Table 4.

Age, sex and clinical characteristics of ARI/ILI patients and their positivity for human coronaviruses and influenza viruses.

Collected Variable All Patients ARI./ILI Patients positive Patients HCoVs Positive Negative for All Viruses Tested
Influenza Virus A Influenza Virus B All HCoVs Positive Patients* p-Value Single HCoV Co-Pathogen p-Value p-Value
n % n % n % n % FluA/HCoV FluB/HCoV n % n % singleHCoV/ Copathogen n % HCoV/ Negative
Number of HCoVs positive patients 1389 100.0 328 23.6 212 15.3 105 7.6 82 78.1 23 21.9 561 40.4
Age Median Age (years) 34 36 28.5 34 / / 39.5 11.0 / 36.0 /
Mean Age (Min-Max) (years) 34.96 (0.08–97.0) 34.53 (0.08–89) 31.02 (0.67–91) 34.61 (0.08–90) 37.43 (0.50–90.0) 24.5 (0.08–80) 36.73 (0.25–90)
Age IQR (years) 13–53 13–51 10–48 11–52 16.0–53.5 3.5–44.0 17.0–54.0
n % n % n % n % p-Value n % p-Value n % p-Value n %
0–14 years 378 27.2 88 26.8 73 34.4 30 28.6 0.00005 0.908 0.535 18 22.0 0.00137 12 52.2 0.00005 0.008 124 22.1 0.406
15–29 years 210 15.1 42 12.8 37 17.5 14 13.3 13 15.9 1 4.3 0.295 93 16.6
30–44 years 303 21.8 84 25.6 42 19.8 21 20.0 17 20.7 4 17.4 1 135 24.1
45–59 years 268 19.3 69 21.0 34 16.0 25 23.8 22 26.8 3 13.0 0.267 104 18.5
60–74 years 149 10.7 32 9.8 16 7.5 10 9.5 8 9.8 2 8.7 1 73 13.0
≥ 75 81 5.8 13 4.0 10 4.7 5 4.8 4 4.9 1 4.3 1 32 5.7
Sex Female 758 54.6 184 56.1 110 51.9 51 48.6 0.782 0.216 0.633 44 53.7 0.435 7 30.4 0.0174 0.06 311 55.4 0.202
Male 631 45.4 144 43.9 102 48.1 54 51.4 38 46.3 16 69.6 250 44.6
n % NA n % NA n % NA n % NA n % NA n % NA n % NA
Symptoms Fever 1298 95.2 25 321 98.5 2 205 97.2 1 94 91.3 2 0.00131 0.0439 72 88.9 1 22 100.0 1 0.198 513 93.4 12 0.400
Cough 1087 87.8 151 247 92.2 60 173 88.7 17 84 89.4 11 0.397 1 66 90.4 9 18 85.7 2 0.688 418 82.9 57 0.128
Sore throat 659 53.2 151 125 46.6 60 101 51.8 17 64 68.1 11 0.000465 0.011 55 75.3 9 9 42.9 2 0.006 267 53.0 57 0.0068
Dyspnea 241 19.5 151 49 14.9 0 31 14.6 0 32 30.5 0 0.000817 0.00152 29 35.4 0 3 13.0 0 0.04 91 16.2 0 0.000963
Rhinorrhea 932 75.3 151 206 76.9 60 150 76.9 17 83 88.3 11 0.017 0.0257 64 87.7 9 19 90.5 2 1 355 70.4 57 0.000201
Myalgia 666 69.0 424 123 70.7 154 120 74.1 50 52 70.3 31 1 0.533 41 71.9 25 11 64.7 6 0.561 288 71.5 158 0.889
Headache 863 69.7 151 194 72.4 60 147 75.4 17 73 77.7 11 0.343 0.769 59 80.8 9 14 66.7 2 0.233 346 68.7 57 0.0866
Malaise 85 12.0 681 26 12.7 124 13 14.3 121 3 3.2 11 0.0104 0.00844 2 2.7 9 1 4.8 2 0.536 36 14.9 319 0.002
Conjunctivitis 345 24.8 0 67 20.4 0 59 27.8 0 32 30.5 0 0.0446 0.692 24 29.3 0 8 34.8 0 0.616 141 25.1 0 0.275
Vomiting 151 10.9 0 32 9.8 0 20 9.4 0 15 14.3 0 0.208 0.252 12 14.6 0 3 13.0 0 1 66 11.8 0 0.514
Diarrhea 154 11.1 0 23 7.0 0 23 10.8 0 10 9.5 0 0.401 0.845 9 11.0 0 1 4.3 0 0.442 68 12.1 0 0.512
Other symptoms 184 21.0 512 44 16.2 56 21 18.3 97 18 26.9 38 0.0521 0.192 15 30.6 33 3 16.7 5 0.757 82 25.0 233 0.759
Anormal lung auscultation 88 26.3 1055 24 25.3 233 8 17.0 165 8 38.1 84 0.282 0.0709 6 46.2 69 2 25.0 15 0.4 34 27.2 436 0.309
Other variables Risk factors 321 23.5 22 59 18.3 6 41 19.4 1 16 15.2 0 0.555 0.4 13 15.9 0 3 13.0 0 1 145 26.4 11 0.0182
Oseltamivir 241 18.0 49 88 27.7 10 29 14.0 5 14 13.6 2 0.00348 1 12 15.0 2 2 8.7 0 0.73 88 16.4 26 0.558
Antibiotics 173 13.3 86 43 14.2 25 18 8.8 7 10 9.9 4 0.31 0.833 7 8.9 3 3 13.6 1 0.45 73 14.1 43 0.338
Hospitalization 39 2.9 32 12 3.8 10 7 3.4 5 2 1.9 0 0.532 0.7 2 2.4 0 0 0.0 0 1 15 2.7 10 1

* Overall HCoV infections also include strains without species determination (N = 20).