CKD | Chronic Kidney Disease |
ESRD | End-stage renal disease |
ED | Endothelial dysfunction |
ECs | Endothelial cells |
eGFR | Estimated glomerular filtration rate |
PAMPs | Pathogen-associated molecular patterns |
DAMPs | Damage-associated molecular patterns |
HMGB1 | High-mobility group box 1 |
ICAM-1 | Intercellular Adhesion Molecule 1 |
VCAM-1 | Vascular Cell Adhesion Molecule 1 |
MCP-1 | Monocyte chemoattractant protein-1 |
VWF
ATP |
Von Willebrand Factor Adenosine 5’-triphosphate |
LDL
NET CASP1 |
Low density lipoproteins Neutrophil extracellular traps Caspase-1 |
IS | Indoxyl sulfate |
PCS | p-Cresyl sulfate |
IAA | Indole-3 acetic acid |
TMAO | Trimethylamine N-oxide |
ROS | Reactive oxygen species |
AGEs | Advanced glycation end-products |
AHR | Aryl hydrocarbon receptor |
MAPK | Mitogen-activated protein kinase |
ELAM-1 | Endothelial-leukocyte adhesion molecule |
NFκB | Nuclear factor kappa B |
TLR4 | Toll-like receptor 4 |
NLRP3, NALP3 | NOD-like receptor prying domain-containing-3 |
SIRT1 | Sirtuin 1 |
KLF2 | Krüppel-like factor 2 |
KLF4 | Krüppel-like factor 4 |
eNOS | Endothelial nitric oxide synthase |
VE-cadherin | Vascular endothelial cadherin |
ZO1 | Zonula occludens |
EPCs | Endothelial progenitor cells |
MV | Microvesicles |
EMV | Endothelial microvesicles |
ECM | Extracellular matrix |
TF | Tissue factor |
IL | Interleukin |
CECs | Circulating endothelial cells |
PMNs | Polymorphonuclear leukocytes |
TLRs | Toll-like receptors |
RTT | Renal replacement therapy |
PRRs | Pattern recognition receptors |
ASC | Apoptosis-associated speck-like protein containing a CARD |
TXNIP | Thioredoxin-interacting protein |
GSDMD | Gasdermin D |
VSMCs | Vascular smooth muscle cells |
MMPs | Matrix metalloproteinases |
TNF-α | Tumor necrosis factor alpha |
LPSs | Lipopolysaccharides |
HD | Hemodialysis |
HDL | High-density lipoprotein |
SCFA | Short-chain fatty acids |
GI | Gastrointestinal tract |
CV | Cardiovascular |
PMPs | Platelet microparticles |