Table 1.
The fold change in immune- or inflammation-related differentially expressed genes (DEGs) induced by LPS or PLL, compared with non-treatment.
| Gene Symbol | Gene Description | Fold Change * | |
|---|---|---|---|
| LPS | PLL | ||
| Cytokines and Chemokines | |||
| CCL20 | C-C motif chemokine 20 | 802.17 | 1266.00 |
| CCL5 | C-C motif chemokine 5 | 9.29 | 13.80 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 | 6.34 | 9.52 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 20.07 | 32.26 |
| CXCL8 (IL-8) | interleukin-8 | 26.24 | 54.95 |
| IL1A (IL-1α) | interleukin-1 alpha | 3.73 | 5.76 |
| IL1B (IL-1β) | interleukin-1 beta | 310.00 | 300.00 |
| IL6 | interleukin-6 | 5.06 | 8.06 |
| NFKBIA | NF-kappa-B inhibitor alpha | 2.42 | 3.19 |
| TNF | tumor necrosis factor | 34.00 | 62.00 |
| CSF2 | granulocyte-macrophage colony-stimulating factor | – | 4.11 |
| Flt3lg | fms-related tyrosine kinase 3 ligand isoform X2 | – | 2.08 |
| TNFSF10 | tumor necrosis factor ligand superfamily member 10 | – | 2.20 |
| Another Immune Associated DEGs | |||
| C1S | TPA: complement C1s subcomponent | 2.13 | - |
| C2 | complement C2 | 4.44 | 6.44 |
| CFB | complement factor B | 52.12 | 132.50 |
| ISG15 | ubiquitin-like protein ISG15 | 2.16 | 11.60 |
| MMP9 | matrix metalloproteinase-9 | 2.85 | 4.89 |
| MAP2K6 | dual specificity mitogen-activated protein kinase kinase 6 | – | 0.46 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 isoform X2 | – | 2.77 |
| CD14 | monocyte differentiation antigen CD14 isoform X2 | – | 5.77 |
| ASAP3 | arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 | – | 3.20 |
| TLR3 | toll-like receptor 3 isoform X1 | – | 2.53 |
| MEFV | pyrin isoform X1 | – | 10.67 |
| DHX58 | probable ATP-dependent RNA helicase DHX58 | – | 2.95 |
| DDX58 | probable ATP-dependent RNA helicase DDX58 | – | 2.10 |
| ZBP1 | TPA: Z-DNA binding protein 1-like | – | 3.47 |
| CD3G | T-cell surface glycoprotein CD3 gamma chain | – | 0.47 |
| TNFAIP3 | tumor necrosis factor alpha-induced protein 3 | – | 2.17 |
* Data obtained by RNA-Seq and presented as the fold change (FC) of the DEGs induced by lipopolysaccharide (LPS) and co-stimulation with peptidoglycan (PGN), lipoteichoic acid (LTA), and LPS (PLL). For all the FCs shown, the false-discovery rate (FDR) is <0.05 and |log2 FC| > 1. “–” indicates that the gene did not belong to DEGs.