Figure 3.
(a) Kaplan–Meier survival analysis for comparisons of proportion of progression to AD between hypertensive (n = 6) and non-hypertensive (n = 26) patients in Clock C carriers group. Proportion of progression was higher in hypertensive group (50.00%) compared to non-hypertensive (11.50%). The pairwise log rank comparisons showed significant difference in survival distributions for the hypertensive vs. non-hypertensive (χ2 = 5.77, p = 0.017). (b) Kaplan–Meier survival analysis for comparisons of proportion of progression to AD between hypertensive (n = 9) and non-hypertensive (n = 26) patients in Clock non C carriers group. The pairwise log rank comparisons showed no significant difference in survival distributions for the hypertensive vs. non-hypertensive (χ2 = 0.323, p = 0.570). * For censored cases (non converters) conversion time indicates follow-up time.