Table 3.
Baseline cognitive function and functional ability data of active and placebo intervention groups.
| Variable | Active (n = 10) Median (IQR) |
Placebo (n = 9) Median (IQR) |
Sig. |
|---|---|---|---|
| Global cognition | |||
| MoCA | 21.0 (18.8–24.0) | 21.0 (19.0–24.0) | 0.842 |
| RBANS immediate memory | 78.0 (64.0–82.5) | 85.0 (72.5–98.5) | 0.156 |
| RBANS visuospatial | 101.0 (92.0–109.0) | 100.0 (91.5–110.5) | 0.842 |
| RBANS language | 89.0 (84.5–93.0) | 88.0 (82.0–92.0) | 0.661 |
| RBANS attention | 81.0 (71.0–98.5) | 79.0 (77.0–89.5) | 0.905 |
| RBANS delayed memory | 75.0 (47.0–87.5) | 71.0 (58.0–87.0) | <0.999 |
| RBANS total scale | 78.0 (75.0–84.0) | 82.0 (73.5–85.0) | 0.497 |
| 4 mountains test | 6.5 (6.0–7.8) | 7.0 (5.5–7.5) | 0.905 |
| Comprehension | |||
| Latency | 1165.9 (812.9–1322.2) | 1152.8 (991.75–1301.5) | 0.842 |
| Total errors | 0 | 0 | 0.720 |
| Working memory | |||
| Between errors | |||
| Stage 4 | 1.0 (0.8–2.0) | (1.0–2.5) | 0.497 |
| Stage 6 | 6.0 (4.3–7.5) | 6.0 (6.0–7.0) | 0.497 |
| Stage 8 | 16.0 (15.0–17.0) | 12.5 (11.0–14.0) | 0.006 |
| All stages | 21.5 (21.0–26.5) | 20.0 (18.0–22.5) | 0.182 |
| Total errors | |||
| Stage 4 | (0.8–2.0) | 2.0 (1.0–2.5) | 0.447 |
| Stage 6 | 6.0 (4.3–7.5) | 6.0 (6.0–7.0) | 0.497 |
| Stage 8 | 16.5 (15.0–17.3) | 13.0 (11.0–14.8) | 0.012 |
| All stages | 21.5 (21.0–28.3) | 22.0 (18.0–22.5) | 0.447 |
| Strategy | 10.0 (9.0–11.3) | 9.0 (8.5–10.0) | 0.315 |
| Reaction time | |||
| Simple reaction time | 382.4 (370.7–463.6) | 372.9 (354.9–411.5) | 0.356 |
| Simple movement time | 296.5 (249.6–336.6) | 318.9 (277.3–352.3) | 0.497 |
| Simple error score | 2.0 (0.8–3.5) | 1.0 (0–3.0) | 0.400 |
| Five-choice reaction time | 458.1 (415.7–510.3) | 435.1 (406.5–485.5) | 0.549 |
| Five-choice movement time | 310.3 (286.5–367.0) | 313.0 (294.2–335.4) | <0.999 |
| Five-choice error score | 0.5 (0–1.3) | 1.0 (0–2.0) | 0.549 |
| Episodic memory | |||
| First attempt memory score | 4.0 (3.5–5.5) | 4.0 (2.5–6.5) | 0.905 |
| No. patterns reached | 6.0 (4.0–6.5) | 6.0 (4.0–6.0) | 0.549 |
| Total errors adjusted stage 2 | 0 (0–0.3) | 0 (0–0.5) | 0.905 |
| Total errors adjusted stage 4 | 6.0 (2.3–8.8) | 6.0 (0.5–9.5) | 0.780 |
| Total errors adjusted stage 6 | 18.5 (12.3–20.0) | 20.0 (14.5–20.0) | <0.999 |
| Total errors adjusted stage 8 | 28.0 (25.3–28.0) | 28.0 (28.0–28.0) | 0.720 |
| Total errors adjusted all stages | 52.5 (42.8–59.0) | 48.0 (45.0–58.0) | 0.780 |
| Functional ability | |||
| BADLS | 20.0 (15.5–20.0) | 20.0 (20.0–20.0) | 0.243 |
| AQ | 8.0 (4.8–13.8) | 5.0 (2.5–8.0) | 0.113 |
Data displayed are median (inter quartile range); MoCA: Montreal Cognitive Assessment; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status; BADLS: Bristol Activities of Daily Living Scale; AQ: Alzheimer’s Questionnaire.