Table A1.
Composition of formulation used in CARES Trial 1 (mg/capsule).
| Compound Family | Compound | Formulated | Actual |
|---|---|---|---|
| Fatty Acids | Palmitic acid (16:0) | 55.44 ± 1.39 | |
| Palmitoleic acid (16:1) | 0.84 ± 0.02 | ||
| Stearic acid (18:0) | 31.60 ± 1.02 | ||
| Oleic acid (18:1n9c) | 40.24 ± 0.74 | ||
| Vaccenic acid (18:1n9t) | 6.26 ± 0.06 | ||
| Linoleic acid (18:2n6) | 28.57 ± 0.78 | ||
| α-Linolenic acid (18:3n3) | 1.55 ± 0.03 | ||
| Eicosenoic acid (20:1n7, n9, n11) | 41.16 ± 0.94 | ||
| Homo-γ-linolenic acid (20:3) | 1.45 ± 0.04 | ||
| Arachidonic acid (20:4n6) | 14.20 ± 0.20 | ||
| Eicosapentaenoic acid (20:5n3) | 45 | 47.89 ± 0.69 | |
| Docosapentaenoic acid (22:5n3) | 11.37 ± 0.18 | ||
| Docosahexaenoic acid (22:6n3) | 215 | 258.03 ± 2.75 | |
| Carotenoids | Lutein | 5 | 5.18 ± 0.06 |
| Zeaxanthin | 1 | 1.75 ± 0.03 | |
| meso-zeaxanthin | 5 | 6.48 ± 0.24 | |
| Vitamin E | α-tocopherol | 7.5 | 6.12 ± 0.04 |
| Total mg | 558.15 |
Data presented as mean ± SD. Formulations analyzed in triplicate (three capsules analyzed). Average capsule content calculated gravimetric analysis, 0.666 ± 0.001 g (n = 3).