Figure 1.

Inhibition of A_2BR by PSB1115 protected NEC rats against the loss of body weight. No significant differences in body weight were observed between groups before experiment. NEC results in marked body weight loss after experiment as compared to the control group. However, PSB1115 protects NEC animals against body weight loss. NEC: necrotizing enterocolitis; NECB: necrotizing enterocolitis+BAY60-6583 treatment; NECP: necrotizing enterocolitis+PSB1115 treatment. ^Δp < 0.05 vs. all other groups; ^∗p < 0.001 vs. baseline (before experiment); ^#p < 0.001 vs. the Con group.