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. Author manuscript; available in PMC: 2020 Nov 14.
Published in final edited form as: J Med Chem. 2019 Oct 21;62(21):9471–9487. doi: 10.1021/acs.jmedchem.9b00846

Figure 3. The cell growth inhibition activity of MG-277 is MDM2-independent.

Figure 3.

(A-D) Effect of knockdown of MDM2 on the cell growth inhibitory activity of MI-2103 and MG-277 in MDA-MB-231 and MDA-MB-468 cells after transfection with MDM2 siRNAs (C-D) or non-targeting siRNA control vector (A-B) for 2 days. (E) MDM2 knockdown efficiency was determined by Western blotting analysis.