Figure 1.

Deep-brain imaging as a powerful tool to understand neuroendocrine functioning. Unknowns such as the relationship between the activity of specific neurons and the dynamics of peripheral hormonal secretion (A) or the way newly discovered genetic mutations result in phenotypic changes (B) can be elucidated using in vivo deep brain imaging. Researchers will greatly benefit from real-time visualisation of single neuron calcium activity (C), population calcium activity (D), and will gain insight into the network activity of genetically defined neurons (E).