T31	T111 (26)
In vitro IC50 vs. blood-stage P. falciparum D6/Tm90-C2B:	0.022/228	0.028/5.6
In vivo ED50/ED90 (mg/kg/d) vs. blood-stage P. yoelii:	1.0/1.6	0.045/0.098
In vivo cure (mg/kg×4 days) vs. blood-stage P. yoelii:	80	10
In vivo full protection/cure (mg/kg×3 days) vs. liver-stage P. berghei:	4.0	4.0
In vitro metabolic stability vs. human/mouse (t1/2, min):	12/21	>60/50
In vivo PK (mouse, po): plasma/liver half-life (t1/2, h):	6.00/4.63	23.6/14.0
hERG (% inhibition at 10 μM):	57	5.7
hERG (% inhibition at 10 μM):	57	5.7