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. Author manuscript; available in PMC: 2020 Jul 12.
Published in final edited form as: J Bone Miner Res. 2019 Jan 15;34(4):607–615. doi: 10.1002/jbmr.3636

Table 4.

Proportion of Women with Major Osteoporotic Fractures during 10-year Follow-up who are Identified for Bone Mineral Density Testing under the USPSTF and Canadian Strategies*

Strategy Age Group Total n Identified for screening, n (%) MOF Events, n (%) Sensitivity (95% CI) Specificity (95% CI) Positive Predictive Value (95% CI)
USPSTF All Participants 115257 62546 (54%) 14105 (12%) 72.5 (71.8, 73.3) 48.3 (48.0, 48.6) 16.4 (16.1, 16.6)
50–54 16420 727 (4%) 1032 (6%) 6.7 (5.2, 8.2) 95.7 (95.4, 96.0) 9.5 (7.4, 11.6)
55–59 24523 3654 (15%) 1955 (8%) 21.7 (19.9, 23.5) 85.7 (85.2, 86.1) 11.6 (10.6, 12.6)
60–64 27602 11453 (41%) 2731 (10%) 49.5 (47.6, 51.4) 59.4 (58.8, 60.0) 11.8 (11.2, 12.4)
65–69 24997 24997 (100%) 3544 (14%) 100.0 (–) 0.0 (–) 14.2 (13.7, 14.6)
70–74 15808 15808 (100%) 3111 (20%) 100.0 (–) 0.0 (–) 19.7 (19.1, 20.3)
75–79 5907 5907 (100%) 1732 (29%) 100.0 (–) 0.0 (–) 29.3 (28.2, 30.5)
Canadian All Participants 115257 82599 (72%) 14105 (12%) 82.9 (82.2, 83.5) 29.9 (29.6, 30.2) 14.1 (13.9, 14.4)
50–54 16420 8391 (51%) 1032 (6%) 54.4 (51.3, 57.4) 49.1 (48.3, 49.9) 6.7 (6.2, 7.2)
55–59 24523 12373 (50%) 1955 (8%) 55.4 (53.2, 57.6) 50.0 (49.3, 50.6) 8.8 (8.3, 9.3)
60–64 27602 15123 (55%) 2731 (10%) 60.6 (58.8, 62.5) 45.9 (45.2, 46.5) 11.0 (10.5, 11.4)
65–69 24997 24997 (100%) 3544 (14%) 100.0 (–) 0.0 (–) 14.2 (13.7, 14.6)
70–74 15808 15808 (100%) 3111 (20%) 100.0 (–) 0.0 (–) 19.7 (19.1, 20.3)
75–79 5907 5907 (100%) 1732 (29%) 100.0 (–) 0.0 (–) 29.3 (28.2, 30.5)
*

Major osteoporotic fractures (MOF) are defined as adjudicated hip fracture or self-report fracture of lower arm/wrist, spine/back, or upper arm/shoulder. USPSTF denotes United States Preventive Services Task Force