Table 5.

Proportion of Women with Major Osteoporotic Fractures during 10-year Follow-up who are Identified for Treatment under the NOF and Canadian Strategies^*

Strategy	Age Group	Total n	Identified for treatment, n (%)	MOF Events, n (%)	Sensitivity (95% CI)	Specificity (95% CI)	Positive Predictive Value (95% CI)
NOF	All Participants	7926	2184 (28%)	1034 (13%)	50.3 (47.2, 53.3)	75.9 (74.8, 76.9)	23.8 (22.0, 25.6)
	50–54	1255	93 (7%)	79 (6%)	10.1 (3.3, 16.9)	92.8 (91.3, 94.3)	8.6 (2.8, 14.4)
	55–59	1660	234 (14%)	138 (8%)	29.0 (21.3, 36.7)	87.3 (85.6, 88.9)	17.1 (12.2, 22.0)
	60–64	1794	412 (23%)	189 (11%)	37.6 (30.6, 44.5)	78.8 (76.8, 80.8)	17.2 (13.6, 20.9)
	65–69	1729	604 (35%)	256 (15%)	50.0 (43.8, 56.2)	67.7 (65.3, 70.1)	21.2 (17.9, 24.5)
	70–74	1100	553 (50%)	250 (23%)	68.8 (63.0, 74.6)	55.2 (51.8, 58.5)	31.1 (27.2, 35.0)
	75–79	388	288 (74%)	122 (31%)	82.8 (76.0, 89.6)	29.7 (24.2, 35.2)	35.1 (29.5, 40.6)
Canadian	All Participants	7926	826 (10%)	1034 (13%)	24.7 (22.0, 27.3)	91.7 (91.1, 92.4)	30.9 (27.7, 34.0)
	50–54	1255	6 (<1%)	79 (6%)	1.3 (0.0, 3.8)	99.6 (99.2, 99.9)	16.7 (0.0, 59.5)
	55–59	1660	29 (2%)	138 (8%)	4.3 (0.9, 7.8)	98.5 (97.9, 99.1)	20.7 (5.0, 36.4)
	60–64	1794	119 (7%)	189 (11%)	14.8 (9.7, 19.9)	94.3 (93.2, 95.5)	23.5 (15.8, 31.3)
	65–69	1729	269 (16%)	256 (15%)	27.0 (21.5, 32.4)	86.4 (84.7, 88.2)	25.7 (20.4, 30.9)
	70–74	1100	261 (24%)	250 (23%)	35.2 (29.2, 41.2)	79.6 (76.9, 82.4)	33.7 (27.9, 39.5)
	75–79	388	142 (37%)	122 (31%)	51.6 (42.6, 60.6)	70.3 (64.8, 75.8)	44.4 (36.1, 52.6)

^*Major osteoporotic fractures (MOF) are defined as adjudicated hip fracture or self-report fracture of lower arm/wrist, spine/back, or upper arm/shoulder. NOF denotes National Osteoporosis Foundation