Fig. 3. CTGF & PDGF-BB expressions in liver fibrosis after bile duct ligation were decreased in BDL+TZD rats. Representative PDGF-BB (A) & CTGF (B) immunostaining positive area in sham, BDL and BDL+TZD rats (arrows). Significantly lower PDGF-B chain & CTGF gene expressions in BDL+TZD rats compared to BDL rats upon qPCR assessment (C). CTGF: connective tissue growth factor, PDGF: platelet-derived growth factor, BDL: bile duct ligation, TZD: thiazolidinedione, qPCR: quantitative polymerase chain reaction. (A) PDGF-BB immunostaining left to right, top to bottom: x40, only zoomed in of the square in the ×40 (not via microscope), ×40, and ×40. (B) CTGF immunostaining left to right, top to bottom: ×40, only zoomed in of the square in the x40 (manual zoomed in not via microscope), ×40 and ×40. ^*p<0.05.