Table 2.

Age and Scan Quality Adjusted Change Rates of Ganglion Cell Complex Thickness and Vessel Density in Healthy, Pre-perimetric Glaucoma and Primary Open Angle Glaucoma Eyes

	A. Healthy	B. Pre-perimetric Glaucoma	C. POAG	Pairwise Comparisons P Value#
	Estimate (95% CI); P value*	Estimate (95% CI); P value*	Estimate (95% CI); P value*	A vs. B	B vs. C	A vs. C
Ganglion Cell Complex Thickness Change Rate (μm / year)
Whole Image	−0.70 (−1.13, −0.27); 0.002	−1.08 (−1.37, −0.79); <0.001	−1.18 (−1.38, −0.99); <0.001	0.150	0.562	0.045
Perifoveal	−0.65 (−1.07, −0.23); 0.003	−1.08 (−1.37, −0.79); <0.001	−1.11 (−1.31, −0.92); <0.001	0.100	0.848	0.051
Vessel Density Change Rate (% / year)
Whole Image	−0.76 (−1.28, −0.25); 0.004	−0.93 (−1.26, −0.59); <0.001	−1.35 (−1.58, −1.11); <0.001	0.597	0.043	0.042
Perifoveal	−0.66 (−1.22, −0.11); 0.021	−0.75 (−1.12, −0.39); <0.001	−1.19 (−1.44, −0.93); <0.001	0.791	0.056	0.095

POAG = primary open angle glaucoma; CI = confidence interval.

^*P value represents whether the mean rate of change is significantly different from zero;

^#P value represents whether the mean rate of change is significantly different between groups. Values with statistical significance are shown in bold.