. Author manuscript; available in PMC: 2021 Aug 1.

Published in final edited form as: Ophthalmology. 2020 Jan 13;127(8):1043–1052. doi: 10.1016/j.ophtha.2019.12.030

Table 3.

Normalized Age and Scan Quality Adjusted Rates of Change in Ganglion Cell Complex Thickness and Vessel Density in Healthy, Pre-perimetric Glaucoma, and Primary Open Angle Glaucoma Eyes

	Healthy	Pre-Perimetric Glaucoma	POAG

	Estimate (95% CI)	Estimate (95% CI)	Estimate (95% CI)
Normalized Change Rates of Whole Image (%/year)
Vessel Density	−2.50 (−4.17,−0.84)	−3.85 (−6.04, −1.66)	−7.12 (−8.36, −5.88)
GCC Thickness	−1.53 (−3.10, 0.04)	−2.29 (−4.33, −0.25)	−2.13 (−3.35, −0.90)
P Value	0.384	0.303	<0.001
Normalized Change Rates of Perifoveal (%/year)
Vessel Density	−1.62 (−3.38, 0.13)	−2.88 (−5.16, −0.60)	−5.99 (−7.23, −4.75)
GCC Thickness	−1.34 (−3.00, 0.32)	−2.08 (−4.21, 0.05)	−1.87 (−3.09, −0.65)
P Value	0.811	0.612	<0.001

POAG = primary open angle glaucoma; CI = confidence interval; GCC = ganglion cell complex.

Normalized rates are shown in %/year, annual percent change of dynamic range. Values with statistical significance are shown in bold.