Table 1:

Thematic and topical areas considered for this perspective.

THEMATIC AREAS	Novel Products and Non-traditional organisms	Pushing past the limits of biochemical synthesis	Bioprocess development for individualized medicine	Forward engineering for cellular and biomolecular control	Engineering to understand & exploit new biology
Topical Area (Green - Selected; Blue - Unselected)	Non-model organism development	Combining chemical catalysis with biochemical conversion	Bioprocess development for individualized medicine	Integration of mechanistic based models with data driven approaches for protein- and cell-based engineering	The biology and biotechnology of extracellular vesicles
	Valorization of waste streams	Dynamic spatial assembly of metabolons	Integrating biotherapeutic products and medical devices	Transforming cellular control and predictable cell behaviors through synthetic biology	Building and exploiting interface between electronics and biology
	Biochemical engineering opportunities in food & beverage production	Consortia & Co-cultures – New modality for synthesis	Gene Therapy: The next leap in Biopharma Technology	Genetically encoded biosensors
	Point of care cell-free production modalities			Intgrating computational and experimental protein design
	Chassis development for plant medicinal pathways			Melding heterogeneous biological systems data into a decision framework