. Author manuscript; available in PMC: 2021 May 1.

Published in final edited form as: NMR Biomed. 2020 Jan 13;34(5):e4206. doi: 10.1002/nbm.4206

Table 3:

Repeatability coefficient (C_R) and variance (σ²) of ADC_exp values calculated for different acquisition schemes and acquisition times, in VOI_PCC and VOI_CR. Power analysis can be performed using the σ² values reported in the table and Equation 4.

VOI	Metabolite	12 minute acquisition (scheme b_[0,1,2])		7 minute acquisition (scheme b_[0,2])		4 minute acquisition (scheme b_[0,2])
		C_R (%mean) (μm²/ms)	σ² (x10⁻⁴) (μm⁴/ms²)	C_R (%mean) (μm²/ms)	σ² (x10⁻⁴) (μm⁴/ms²)	C_R (%mean) (μm²/ms)	σ² (x10⁻⁴) (μm⁴/ms²)
VOI_PCC	tNAA	0.015 (12%)	0.3	0.026 (20%)	0.9	0.016 (13%)	0.3
	tCr	0.023 (20%)	0.7	0.032 (26%)	1.3	0.030 (25%)	1.1
	tCho	0.022 (20%)	0.6	0.040 (37%)	2.1	0.025 (23%)	0.8
	mIns	0.040 (37%)	2.1	0.066 (59%)	5.7	0.050 (46%)	3.3
VOI_CR	tNAA	0.042 (27%)	2.3	0.042 (26%)	2.3	0.045 (27%)	2.6
	tCr	0.040 (24%)	2.1	0.043 (25%)	2.4	0.052 (29%)	3.5
	tCho	0.044 (33%)	2.6	0.046 (33%)	2.7	0.050 (34%)	3.2
	mIns	0.104 (75%)	14.1	0.085 (62%)	9.4	0.101 (67%)	13.4