Table 4.

Differential effects of regional cortical thickness by group on processing speed.

Brain region (CT)	Group*Brain Term q-val	Control slope	Control q-val	Control R2	22qDEL slope	22qDEL q-val	22qDEL R2	22qDUP slope	22qDUP q-val	22qDUP R2
Inferior parietal gyrusa,b	0.04	−45.4	4.70E-04	0.31	53.7	0.85	0.01	76.4	0.76	0.16
Insulaa,b	0.02	−35.2	2.80E-03	0.25	56.7	0.13	0.12	43.1	0.93	0.03
Lateral orbitofrontal gyrusa,b	0.04	−33.7	3.90E-04	0.32	42.1	0.76	0.03	44	0.91	0.04
Medial orbitofrontal gyrusa,b	0.02	−36.1	1.30E-04	0.38	44.3	0.76	0.02	47.5	0.87	0.05
Posterior cingulate gyrusa,b	0.02	−40	1.30E-03	0.27	48.7	0.8	0.02	71.6	0.67	0.28
Rostral anterior cingulate gyrusa,b	0.02	−28.1	2.80E-03	0.35	37.4	0.7	0.04	50.9	0.7	0.24
Rostral middle frontal gyrusa	0.02	−42.2	1.30E-04	0.39	49.2	0.84	0.01	62.3	0.85	0.08
Superior frontal gyrusa	0.03	−39.7	8.00E-04	0.29	54.8	0.51	0.06	53.3	0.93	0.03

The "Group-by-brain Term q-value" column includes the q-value of the interaction term for the model: processing speed ~ group + brain + group * brain. The subsequent columns include the slope, FDR-corrected q-value, and R² terms for the within-group model for each group: processing speed ~ brain. Post-hoc, pairwise Tukey tests showed that the relationships between processing speed and CT were different between controls and each of the CNV groups, except for the rostral middle frontal gyrus and superior frontal gyrus for which the duplication group did not differ significantly from the control group.

^acorrected 22qDEL-CON difference

^bcorrected 22qDUP-CON differences

^ccorrected 22qDEL-22qDUP difference.