Table 2.
Measured ramp force parameters for KIF3 motors
| Motor | FDetachment, pN | FMaximum, pN | FStall, pN | Stall, % |
| KIF3AB | 3.7 ± 1.4 | 4.2 ± 1.4 | 5.2 ± 0.2 | 10 |
| KIF3AA | 3.1 ± 1.0 | 3.3 ± 1.1 | 3.8 ± 0.1 | 13 |
| KIF3CC | 1.5 ± 0.4 | 1.6 ± 0.4 | — | — |
| KIF3AC | 1.9 ± 0.5 | 2.3 ± 0.6 | 2.6 ± 0.5 | 14 |
| KIF3ACΔ11 | 1.9 ± 0.7 | 2.4 ± 1.2 | 2.3 ± 0.3 | 13 |
Table of detachment, maximum, and stall force and stall percentage for KIF3AB, KIF3AA, KIF3CC, KIF3AC, and KIF3ACΔL11. Displayed values are means ± SD. Maximum force is defined as the largest force value over baseline that occurs between the beginning of the force ramp and the detachment event. The stall force is defined as the mean force over the final 70 ms of an event that comes to a stall, where a stall is defined as a force plateau in which the SD of the force is less than or equal to 5% of the mean force over that window (37). Dashes represent parameters that were not observed. Measured parameters for KIF3AC and KIF3ACΔL11 were compared through an unpaired student’s t test with an α-reliability level of 0.05, and the differences between KIF3AC and KIF3ACΔL11 for Fdetach, Fmax, and Fstall were not significant (P = 1, 0.36, and 0.10 respectively). Measured detachment forces of KIF3AB, KIF3AA, KIF3AC, and KIF3CC were compared through an unpaired Student’s t test with an α-reliability level of 0.05, and all differences were highly significant (P < 0.0001). Stall % was compared for KIF3AC and KIF3ACΔL11 using the “N − 1” χ2 test, and no significant difference was observed (P = 0.81).