Table 3.
Reasons for Discontinuing a Previous DMT
Reasons for Discontinuing a DMT | n | % |
---|---|---|
Unchanged or increased number of relapses during 12 months compared with the previous treatment | 92 | 25.1% |
MRI activity defined as 2 or more new T2 lesions and 1 or more T1 Gd+ lesions | 91 | 24.8% |
Increase of 1 point in EDSS during 12 months before end of treatment | 65 | 17.7% |
Patient request | 13 | 3.5% |
Administrative reasons | 13 | 3.5% |
Immunological contraindication | 11 | 3.0% |
Absence of MxA protein expression evaluated every 2 years from the start of treatment (only for interferons) | 9 | 2.5% |
Other | 39 | 10.6% |
Unknown | 34 | 9.3% |
Total | 367 | 100% |