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. 2020 Jul 7;14:1129–1135. doi: 10.2147/PPA.S254427

Table 3.

Reasons for Discontinuing a Previous DMT

Reasons for Discontinuing a DMT n %
Unchanged or increased number of relapses during 12 months compared with the previous treatment 92 25.1%
MRI activity defined as 2 or more new T2 lesions and 1 or more T1 Gd+ lesions 91 24.8%
Increase of 1 point in EDSS during 12 months before end of treatment 65 17.7%
Patient request 13 3.5%
Administrative reasons 13 3.5%
Immunological contraindication 11 3.0%
Absence of MxA protein expression evaluated every 2 years from the start of treatment (only for interferons) 9 2.5%
Other 39 10.6%
Unknown 34 9.3%
Total 367 100%