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Effect of MTXNLCs on Organ Weight in IMQ-Induced Psoriasis
| Group | Organ Weight (mg) | |||
|---|---|---|---|---|
| Ear Weight | Lymph Node | Spleen | Thymus | |
| Normal | 3.3±0.48 | 24±3.9 | 64±14 | 50±6.6 |
| IMQ | 5.0±0.41### | 30±2.0### | 166±10### | 60±4.7### |
| IMQ+MTX Carbopol gel (100) | 3.3±0.48*** | 24±1.5*** | 159±12*** | 48±3.7*** |
| IMQ+MTXNLCs (100) | 3.0±0.41*** | 18±1.9*** | 108±10*** | 37±4.6*** |
Notes: Data were represented as mean±SEM. Post-test Bonferroni post hoc test. ***p<0.001 as compared with the IMQ and ###p<0.001 is compared with normal.
