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. 2020 Jul 7;13:303–316. doi: 10.2147/JIR.S254879

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© 2020 Yao et al.

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HUMSC-Exos inhibited rat fibroblast proliferation and fibrosis and promoted apoptosis. Rat fibroblasts were treated with HUMSC-Exos in the presence or absence of TGF-β1. (A) Cell proliferation (n = 5 per group). (B) Dead/live analysis (n = 5 per group). (C) Representative images of dead/live cells stained. Scale bar: 50 μm. (D) Cellular immunofluorescence images of COL III and α-SMA. Scale bar: 50 μm. (E) WB images of COL III and α-SMA. (F) Quantification of COL III and α-SMA (n = 3 per group). (G) Quantitative analysis of mRNA for COL III and α-SMA (n = 5 per group). *P < 0.05, **P < 0.01, ***P < 0.001.