Fig. 1.

Clinical course of brothers with compound heterozygous FH

A. Clinical course of older brother

Picture of buttocks with huge xanthoma is illustrated on the left. Clinical course is illustrated in the middle. Blue line indicates total cholesterol level (mg/dl). Images obtained through intravascular ultrasound are illustrated in the right.

B. Clinical course of younger brother

Picture of buttocks with small xanthoma is illustrated on the left. Clinical course is illustrated in the middle. Blue line indicates total cholesterol level (mg/dl). Images obtained through intravascular ultrasound are illustrated in the right.

UAP: unstable angina pectoris; CAG: coronary artery disease; PCI: percutaneous coronary intervention