Table 5. The odds ratio for rapid GFR decline (rapid progression ≥ 5 ml/min/1.73 m2) of different potential confounders in multiple logistic regression.
| All subjects | |||
|---|---|---|---|
| Adjusted OR | 95% CI | P-value | |
| Age (years) | 1.03 | 0.99 to 1.06 | 0.087 |
| Male | 1.57 | 0.88 to 2.78 | 0.127 |
| Body mass index (kg/m2) | 1.21 | 1.11 to 1.32 | < 0.001 |
| RAAS blockers | 2.04 | 1.02 to 4.07 | 0.043 |
| LDL cholesterol (mg/dL) | 1.02 | 1.01 to 1.03 | 0.026 |
| Fasting plasma glucose (mg/dL) | 1.01 | 0.99 to 1.01 | 0.190 |
| CAVI < 8 | Reference | Reference | 1 |
| CAVI 8–8.9 | 2.47 | 0.89 to 6.84 | 0.082 |
| CAVI ≥ 9 | 4.04 | 1.46 to 11.18 | 0.007 |
| Subgroup in subjects with estimated GFR > 60 (mL/min/1.73 m2) | |||
|---|---|---|---|
| Adjusted OR | 95% CI | P-value | |
| Age (years) | 1.06 | 0.99 to 1.13 | 0.081 |
| Male | 1.88 | 0.78 to 4.56 | 0.161 |
| Body mass index (kg/m2) | 1.30 | 1.11 to 1.51 | 0.001 |
| RAAS blockers | 3.92 | 1.28 to 12.04 | 0.017 |
| LDL cholesterol (mg/dL) | 1.01 | 0.99 to 1.02 | 0.206 |
| Fasting plasma glucose (mg/dL) | 1.00 | 0.99 to 1.02 | 0.473 |
| CAVI < 8 | Reference | Reference | 1 |
| CAVI 8–8.9 | 3.45 | 0.88 to 13.48 | 0.075 |
| CAVI ≥ 9 | 6.44 | 1.59 to 26.04 | 0.009 |
CAVI; Cardio-ankle vascular index, RAAS: Renin–angiotensin–aldosterone system