Table 6. Significantly changed miRNAs in patients with unruptured or ruptured IAs as identified with NGS.
| Systematic Name | logFC | P-Value | Description |
|---|---|---|---|
| UA vs. HC | |||
| hsa-miR-96-5p | −3.46 | 0.000 | Down |
| hsa-miR-598-3p | −3.01 | 0.002 | Down |
| hsa-miR-202-3p | −7.23 | 0.004 | Down |
| hsa-miR-660-5p | −1.52 | 0.004 | Down |
| hsa-miR-92a-1-5p | −3.42 | 0.005 | Down |
| hsa-miR-202-5p | −7.22 | 0.007 | Down |
| hsa-miR-1296-5p | 6.77 | 0.007 | Up |
| hsa-miR-17-3p | −6.77 | 0.008 | Down |
| hsa-miR-215-5p | 1.82 | 0.010 | Up |
| hsa-miR-186-3p | −6.70 | 0.011 | Down |
| hsa-miR-873-5p | −6.37 | 0.012 | Down |
| hsa-miR-129-5p | 3.34 | 0.012 | Up |
| hsa-let-7a-3p | −1.41 | 0.017 | Down |
| hsa-miR-99a-3p | −6.55 | 0.019 | Down |
| hsa-miR-200b-3p | 1.55 | 0.020 | Up |
| hsa-miR-671-3p | −5.84 | 0.020 | Down |
| hsa-miR-551b-3p | −6.51 | 0.022 | Down |
| hsa-miR-548aw | −5.94 | 0.023 | Down |
| hsa-miR-3074-5p | 2.55 | 0.025 | Up |
| hsa-miR-376c-3p | −3.18 | 0.026 | Down |
| hsa-miR-144-5p | −1.36 | 0.026 | Down |
| hsa-miR-576-5p | −1.23 | 0.033 | Down |
| hsa-miR-624-5p | −6.09 | 0.034 | Down |
| hsa-miR-4755-5p | 6.35 | 0.035 | Up |
| hsa-miR-3161 | −5.99 | 0.039 | Down |
| RA vs. UA | |||
| hsa-miR-215-5p | −2.42 | 0.000 | Down |
| hsa-miR-145-5p | 2.31 | 0.000 | Up |
| hsa-miR-202-5p | 9.38 | 0.000 | Up |
| hsa-miR-598-3p | 3.43 | 0.000 | Up |
| hsa-miR-451a | 1.74 | 0.000 | Up |
| hsa-miR-96-5p | 3.78 | 0.001 | Up |
| hsa-miR-550a-3p | 7.02 | 0.001 | Up |
| hsa-miR-532-3p | 1.76 | 0.001 | Up |
| hsa-miR-15b-3p | 1.62 | 0.001 | Up |
| hsa-miR-3613-3p | 6.91 | 0.001 | Up |
| hsa-miR-106b-3p | 1.83 | 0.002 | Up |
| hsa-miR-484 | 1.76 | 0.002 | Up |
| hsa-miR-624-5p | 6.65 | 0.002 | Up |
| hsa-miR-208a-3p | 7.82 | 0.003 | Up |
| hsa-miR-502-3p | 2.22 | 0.003 | Up |
| hsa-miR-4454 | 11.05 | 0.003 | Up |
| hsa-miR-202-3p | 8.19 | 0.004 | Up |
| hsa-miR-660-5p | 1.85 | 0.004 | Up |
| hsa-miR-149-5p | 8.44 | 0.004 | Up |
| hsa-miR-589-5p | 2.43 | 0.005 | Up |
| hsa-miR-186-3p | 6.21 | 0.005 | Up |
| hsa-miR-324-3p | 3.32 | 0.005 | Up |
| hsa-miR-4448 | 7.09 | 0.006 | Up |
| hsa-let-7a-3p | 1.41 | 0.007 | Up |
| hsa-miR-30c-5p | 1.56 | 0.008 | Up |
| hsa-miR-583 | −2.59 | 0.025 | Down |
| hsa-miR-4659a-3p | 5.64 | 0.025 | Up |
| hsa-miR-1287-5p | 2.44 | 0.026 | Up |
| hsa-miR-5699-3p | −4.89 | 0.027 | Down |
| hsa-miR-141-3p | −1.08 | 0.028 | Down |
| hsa-miR-1254 | 5.84 | 0.029 | Up |
| hsa-miR-4508 | 6.28 | 0.029 | Up |
| hsa-miR-193b-5p | −1.28 | 0.030 | Down |
| hsa-miR-18b-5p | 5.81 | 0.030 | Up |
| hsa-miR-181a-5p | 1.12 | 0.030 | Up |
| hsa-miR-106b-5p | 1.64 | 0.030 | Up |
| hsa-miR-15b-5p | 1.06 | 0.030 | Up |
| hsa-miR-548q | 2.67 | 0.030 | Up |
| hsa-miR-208b-3p | 3.77 | 0.030 | Up |
| hsa-miR-664b-3p | −3.00 | 0.031 | Down |
| hsa-miR-329-3p | 2.07 | 0.031 | Up |
| hsa-miR-92a-1-5p | 2.80 | 0.031 | Up |
| hsa-miR-4660 | 5.42 | 0.032 | Up |
| hsa-miR-1307-5p | 2.64 | 0.032 | Up |
| hsa-miR-548d-3p | 5.37 | 0.032 | Up |
| hsa-miR-3667-5p | 5.57 | 0.032 | Up |
| hsa-miR-145-3p | 2.26 | 0.032 | Up |
| hsa-miR-7112-3p | −4.67 | 0.033 | Down |
| hsa-miR-3912-3p | −3.36 | 0.033 | Down |
| hsa-miR-675-3p | 5.86 | 0.033 | Up |
| hsa-miR-3613-5p | 1.15 | 0.041 | Up |
| hsa-miR-200c-3p | 1.31 | 0.044 | Up |
| hsa-miR-424-5p | −1.06 | 0.045 | Down |
| hsa-miR-6807-5p | 5.41 | 0.049 | Up |
| RA vs. HC | |||
| hsa-let-7a-2-3p | 4.41 | 0.002 | Up |
| hsa-miR-1245a | 2.86 | 0.004 | Up |
| hsa-miR-208b-3p | 7.58 | 0.006 | Up |
| hsa-miR-4454 | 10.86 | 0.007 | Up |
| hsa-miR-874-5p | −2.42 | 0.009 | Down |
| hsa-miR-6874-3p | −5.10 | 0.009 | Down |
| hsa-miR-1976 | 4.02 | 0.010 | Up |
| hsa-miR-502-3p | 1.79 | 0.012 | Up |
| hsa-miR-145-5p | 1.40 | 0.012 | Up |
| hsa-miR-129-5p | 2.64 | 0.014 | Up |
| hsa-miR-3146 | −2.88 | 0.015 | Down |
| hsa-miR-548h-5p | 6.45 | 0.018 | Up |
| hsa-miR-3529-5p | −2.33 | 0.023 | Down |
| hsa-miR-1296-5p | 5.89 | 0.025 | Up |
| hsa-miR-4448 | 3.68 | 0.025 | Up |
| hsa-miR-1303 | 3.33 | 0.027 | Up |
| hsa-miR-500a-5p | 3.37 | 0.030 | Up |
| hsa-miR-369-5p | −1.64 | 0.032 | Down |
| hsa-miR-3138 | −2.35 | 0.033 | Down |
| hsa-miR-708-5p | 4.29 | 0.033 | Up |
| hsa-miR-4492 | 5.02 | 0.035 | Up |
| hsa-miR-873-5p | 6.49 | 0.008 | Up |
| hsa-miR-766-3p | 6.10 | 0.008 | Up |
| hsa-miR-107 | 1.33 | 0.008 | Up |
| hsa-miR-154-5p | 5.91 | 0.009 | Up |
| hsa-miR-671-3p | 6.01 | 0.009 | Up |
| hsa-miR-4497 | 7.90 | 0.010 | Up |
| hsa-miR-548aw | 6.09 | 0.010 | Up |
| hsa-miR-5683 | −5.05 | 0.011 | Down |
| hsa-miR-3679-3p | −4.45 | 0.011 | Down |
| hsa-miR-483-5p | −1.61 | 0.011 | Down |
| hsa-miR-6874-3p | −4.88 | 0.011 | Down |
| hsa-miR-500a-5p | 6.23 | 0.012 | Up |
| hsa-miR-365a-3p | 2.11 | 0.012 | Up |
| hsa-miR-3187-3p | 5.71 | 0.013 | Up |
| hsa-miR-576-5p | 1.31 | 0.013 | Up |
| hsa-miR-6889-5p | −4.88 | 0.014 | Down |
| hsa-miR-3529-5p | −2.40 | 0.015 | Down |
| hsa-miR-769-5p | 2.92 | 0.015 | Up |
| hsa-miR-188-5p | 6.03 | 0.016 | Up |
| hsa-miR-17-3p | 5.89 | 0.016 | Up |
| hsa-miR-708-5p | 5.11 | 0.016 | Up |
| hsa-miR-214-3p | 6.03 | 0.016 | Up |
| hsa-miR-3614-5p | 5.70 | 0.016 | Up |
| hsa-miR-4714-3p | 6.05 | 0.016 | Up |
| hsa-miR-4491 | 7.45 | 0.017 | Up |
| hsa-miR-3615 | 1.42 | 0.017 | Up |
| hsa-miR-1226-3p | −1.57 | 0.034 | Down |
| hsa-miR-3605-3p | −1.12 | 0.035 | Down |
| hsa-miR-1268a | 5.46 | 0.036 | Up |
| hsa-miR-425-5p | 1.03 | 0.036 | Up |
| hsa-miR-93-3p | 2.34 | 0.036 | Up |
| hsa-miR-1236-5p | −2.72 | 0.037 | Down |
| hsa-miR-3146 | −3.30 | 0.037 | Down |
| hsa-miR-570-3p | 2.18 | 0.038 | Up |
| hsa-miR-362-3p | 4.97 | 0.038 | Up |
| hsa-miR-5193 | 5.30 | 0.039 | Up |
| hsa-miR-30b-5p | 1.37 | 0.039 | Up |
| hsa-miR-363-3p | 1.26 | 0.040 | Up |
| hsa-miR-4742-3p | 5.35 | 0.040 | Up |
| hsa-miR-4734 | −4.42 | 0.041 | Down |
| hsa-miR-4647 | −4.46 | 0.041 | Down |
| hsa-miR-873-3p | 6.08 | 0.041 | Up |
| hsa-miR-19b-2-5p | 5.57 | 0.041 | Up |
| hsa-miR-6752-5p | −4.57 | 0.042 | Down |
| hsa-miR-4511 | 5.22 | 0.042 | Up |
| hsa-miR-548l | 5.28 | 0.042 | Up |
| hsa-miR-200b-3p | −1.08 | 0.043 | Down |
| hsa-let-7c-5p | 1.21 | 0.043 | Up |
| hsa-miR-122-3p | 6.09 | 0.044 | Up |
| hsa-miR-1908-5p | −1.32 | 0.045 | Down |
| hsa-miR-4753-5p | −2.50 | 0.046 | Down |
| hsa-miR-23c | −1.68 | 0.047 | Down |
| hsa-miR-4497 | 4.35 | 0.035 | Up |
| hsa-miR-208a-3p | 3.31 | 0.036 | Up |
| hsa-miR-6803-3p | −2.02 | 0.037 | Down |
| hsa-miR-3136-5p | −2.32 | 0.038 | Down |
| hsa-miR-4511 | 5.19 | 0.043 | Up |
| hsa-miR-4449 | −3.13 | 0.045 | Down |
| hsa-miR-214-3p | 5.95 | 0.046 | Up |
| hsa-miR-1237-3p | −2.53 | 0.048 | Down |
| hsa-miR-6851-3p | 5.63 | 0.048 | Up |
| hsa-miR-133a-3p | 2.44 | 0.049 | Up |
| hsa-miR-6741-3p | −3.53 | 0.018 | Down |
| hsa-miR-452-5p | 3.40 | 0.019 | Up |
| hsa-miR-30d-5p | 1.08 | 0.019 | Up |
| hsa-miR-3074-5p | −2.14 | 0.020 | Down |
| hsa-miR-543 | 5.77 | 0.020 | Up |
| hsa-miR-1228-5p | 2.79 | 0.020 | Up |
| hsa-miR-205-5p | 1.80 | 0.020 | Up |
| hsa-miR-133a-3p | 2.83 | 0.021 | Up |
| hsa-miR-99a-3p | 5.81 | 0.022 | Up |
| hsa-miR-6806-3p | −3.61 | 0.024 | Down |
| hsa-miR-3180-3p | 5.21 | 0.047 | Up |
| hsa-miR-6881-5p | −3.50 | 0.047 | Down |
| hsa-miR-29c-3p | 1.01 | 0.047 | Up |
| hsa-miR-137 | 5.49 | 0.048 | Up |
| hsa-miR-369-3p | 1.79 | 0.048 | Up |
| hsa-miR-6851-3p | 5.67 | 0.048 | Up |
| hsa-miR-653-3p | 4.96 | 0.049 | Up |
| hsa-miR-208b-5p | 5.41 | 0.049 | Up |
| hsa-miR-1180-3p | 2.39 | 0.050 | Up |