Table 4.
Categorical and continuous moderator analyses.
Categorical moderator | k | ES—r | 95% CI | z | p | Q bet, df (p) | I2 | |
---|---|---|---|---|---|---|---|---|
FTD measure a | 14 | −0.23 | [−0.33, −0.12] | −3.99 | <0.001 | 1.90, 1 (0.168) | 75.77 | |
Clinician-rated | 9 | −0.28 | [−0.40, −0.14] | −3.97 | <0.001 | 83.73 | ||
Behaviorally based | 5 | −0.13 | [−0.31, 0.07] | −1.31 | 0.192 | 0.00 | ||
Social function measure b | 17 | −0.21 | [−0.30, −0.12] | −4.34 | <0.001 | 1.15, 2 (0.563) | 72.63 | |
Self-report | 3 | −0.25 | [−0.46, −0.02] | −2.10 | 0.035 | 87.47 | ||
Clinician-rated | 10 | −0.21 | [−0.33, −0.08] | −3.27 | 0.001 | 75.20 | ||
Performance-based | 4 | −0.20 | [−0.38, −0.01] | −1.98 | 0.048 | 40.67 | ||
Study quality | 13 | −0.23 | [−0.33, −0.12] | −3.88 | <0.001 | 3.35, 1 (0.067) | 77.25 | |
High | 6 | −0.28 | [−0.44, −0.11] | −3.16 | 0.002 | 76.44 | ||
Moderate | 7 | −0.19 | [−0.33, −0.04] | −2.40 | 0.016 | 78.72 | ||
Continuous moderator | k | B | R 2 | SE | 95% CI | z | p | I2 c |
%Female | 12 | −0.21 | 0.03 | 0.72 | [−1.62, 1.20] | −0.29 | 0.77 | 78.03 |
Age | 11 | 0.01 | 0.00 | 0.09 | [−0.01, 0.03] | 0.84 | 0.40 | 80.02 |
Total symptoms | 7 | −0.01 | 0.00 | 0.01 | [−0.03, 0.02] | −0.34 | 0.74 | 70.84 |
Positive symptoms | 9 | −0.26 | 0.00 | 0.27 | [−0.79, 0.27] | −0.95 | 0.34 | 82.42 |
Negative symptoms | 9 | 0.07 | 0.00 | 0.18 | [−0.28, 0.42] | 0.42 | 0.68 | 82.42 |
The p-value of Q bet indicates whether the subgroups are significantly different.
Abbreviations: B, regression coefficient; CI, confidence interval; ES, r effect size statistic; I2, extent of between-study variability; k, number of studies used in the calculation of the mean effect size; p, two-tailed p-value associated with the test of statistical significance; Q bet, variance between subgroups; R2, R2 analogue; SE, standard error, z, test for statistical significance of the mean effect size.
For this analysis, one study [98] contributed effect sizes to both clinician-rated and behaviorally-based subgroups.
For this analysis three studies contributed multiple effect sizes.
The I 2 value might be larger than that of the overall main analyses because not all of the studies were included in the moderator analyses.