Figure 1.
OPCs in the ME of Naive Mice
(A) Scheme shows regions analyzed for BrdU+ cells.
(B) BrdU staining in the ME DG, SVZ, CC, Ctx, and St.
(C) Absence of neuronal progenitors (DCX) in the ME and CC compared with DG. Arrows indicate DCX+ BrdU+ cells.
(D) Images show OPCs (NG2) in the DG, CC, SVZ, and ME boxed in (A). Arrows indicate NG2+ BrdU+ cells.
(E) Images show NG2+ PDGFRa+ OPCs.
(F and G) Quantitative analysis of NG2+ BrdU+ cells in the DG, CC, SVZ, and ME as (F) mean number of NG2+ BrdU+ cells/mm2. ∗p = 0.013, ∗∗p = 0.00079, and (G) as their mean percentage of BrdU+. ∗p = 0.0007 (n = 4 for each group).
Scale bar, 50 μm.